分子量：Calculated MW: 32kDa/33kDa/35kDa
Observed MW: 36KDa

细胞定位：Chromosome, Cytoplasm, Nucleus, centromere, cytoskeleton, spindle

稀释方法：WB 1:500 - 1:2000

总结：This gene encodes a member of the Aurora subfamily of serine/threonine protein kinases. The encoded protein is a chromosomal passenger protein that forms complexes with Aurora-B and inner centromere proteins and may play a role in organizing microtubules in relation to centrosome/spindle function during mitosis. This gene is overexpressed in several cancer cell lines, suggesting an involvement in oncogenic signal transduction. Alternative splicing results in multiple transcript variants.