分子量：Calculated MW: 46kDa/86kDa
Observed MW: 87kDa

细胞定位：Cytoplasm, Nucleus, cytoskeleton, spindle

稀释方法：WB 1:500 - 1:2000
IF 1:50 - 1:100

总结：The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.